Active B Complex provides the most biologically active forms and clinically relevant doses of a unique B vitamin combination. Quatrefolic folate provides (6S)-5-Methyltetrahydrofolate acid (MTHF), the active form of folate at the cellular level, the form found in circulation, and the only form able to cross the blood brain barrier. This form of folate bypasses enzymatic conversion by methylene tetrahydrofolate reductase (MTHFR), an enzyme with common genetic polymorphisms known to impair activity. Quatrefolic acid administration has been associated with higher peak (6S)-5-MTHF levels than both folic acid and calcium 5-MTHF, with higher plasma folate levels even in those with high functioning MTHFR polymorphisms.1,2

In addition to superior folate bioavailability, Active B Complex contains superior forms of each B vitamin. Benfotiamine is a lipid soluble form of vitamin B1 with higher bioavailability than thiamine, used in the treatment of diabetic neuropathy because it blocks several hyperglycemic pathways and prevents endothelial dysfunction.3,4,5 Riboflavin 5’-phospate and pyridoxal 5’-phosphate (PLP) are biologically active forms of B2 and B6 – PLP being the most important member of the B6 group, and is the active coenzyme for more than 100 enzymes, bypassing hepatic conversion to an active form.

Active B Complex提供最具生物活性的形式和临床相关剂量的独特B族维生素组合。 Quatrefolic叶酸提供(6S)-5-甲基四氢叶酸(MTHF),叶酸的活性形式在细胞水平,在循环中发现的形式,并且唯一的形式能够穿过血脑屏障。这种形式的叶酸绕过亚甲基四氢叶酸还原酶(MTHFR)的酶促转化,MTHFR是一种具有已知损害活性的常见遗传多态性的酶。与叶酸和5-MTHF钙相比,Quatrefolic acid给药的峰值(6S)-5-MTHF水平更高,即使在具有高功能MTHFR多态性的患者中,血浆叶酸水平也更高.1,2 除了优异的叶酸生物利用度外,活性B复合物还含有各种B族维生素。 Benfotiamine是一种脂溶性形式的维生素B1,具有比硫胺素更高的生物利用度,用于治疗糖尿病神经病变,因为它可以阻断几种高血糖途径并防止内皮功能障碍.3,4,5核黄素5'-磷酸酯和吡哆醛5'-磷酸酯( PLP)是B2和B6的生物活性形式 - PLP是B6组中最重要的成员,并且是超过100种酶的活性辅酶,绕过肝转化为活性形式.

Each Vegetarian Capsule Contains:  
Vitamin B1 (Thiamine Hydrochloride,  
Benfotiamine) 31.69 mg
Vitamin B2 (Riboflavin 5’-Phosphate Sodium) 10 mg
Niacin (Inositol Hexanicotinate) 100 mg
Pantothenic Acid (Calcium d-Pantothenate) 100 mg
Vitamin B6 (Pyridoxal 5-Phosphate) 25 mg
Vitamin B12 (Methylcobalamin) 500 mcg
Folate (from (6S)-5-Methyltetrahydrofolic Acid (MTHF),
Glucosamine Salt, Quatrefolic ® ) 400 mcg
Biotin 250 mcg
Choline (Citrate) 50 mg
Inositol (Inositol, Inositol Hexanicotinate) 50 mg



维生素B1(盐酸硫胺素, Benfotiamine)31.69毫克





维生素B12(Methylcobalamin)500 mcg

叶酸(来自(6S)-5-甲基四氢叶酸(MTHF), 氨基葡萄糖盐,Quatrefolic®)400 mcg

生物素250 mcg



Recommended Use:

1 capsule per day with food or as directed by a health care practitioner.

建议用量: 每日1粒胶囊随餐服用或由保健医生指示。

Active B Complex

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© 2017 by CIMED Integrative Medical Center

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