Estrolief contains key components and vitamins to aid in hormone metabolism and reduce the risk of hormone-sensitive, abnormal cell proliferation via different mechanisms.

  • DIM is the bioactive metabolite of Indole-3-Carbinol (I3C) from cruciferous vegetables. DIM has been shown in studies to better aid in the estrogen metabolism than I3C due to its actions further down the pathway. DIM enhances the estrone conversion to 2-OH-estrone (protective) and decreases the conversion to 4-OH & 16-OH metabolites (persistently estrogenic).
  • SDG (Secoisolariciresinol diglucoside) has a strong affinity to the receptor of 4-, 16-OH estrone. It exerts an "amphiteric effect" to reduce the harmful estrogenic effect of 4-OH & 16-OH estrones by occupying the receptors while alleviating menopausal symptoms.
  • D-glucarate has been shown to inhibit beta-glucuronidase - an enzyme that recycles toxins and hormone metabolites back into the blood stream rather than excreted and, thus, slows down the detoxification process.
  • Formulated with essential coenzymes: 5-MTHF, pyridoxine-5-phosphate, and B12 - to promote the steroids detoxification (ie. methylation, transamination).

Estrolief含有有助于激素代谢的关键成分和维生素,,并通过不同的机制降低激素敏感,异常细胞增殖的风险。 DIM是来自十字花科蔬菜的吲哚-3-甲醇(I3C)的生物活性代谢物。 DIM已经在研究中显示出比I3C更好地帮助雌激素代谢,因为它在该途径中进一步发挥作用。 DIM增强雌酮转化为2-OH-雌酮(保护性)并降低向4-OH和16-OH代谢物(持续雌激素)的转化。 SDG(Secoisolariciresinol diglucoside)对4,16-OH雌酮的受体具有强亲和力。它通过占据受体同时减轻更年期症状,发挥“两性效应”以减少4-OH和16-OH雌酮的有害雌激素作用。 D-葡萄糖酸盐已被证明可以抑制β-葡萄糖醛酸酶 - 一种将毒素和激素代谢物再循环回血液而不是排泄的酶,从而减缓了解毒过程。 配方中含有必需的辅酶:5-MTHF,吡哆醇-5-磷酸和B12-促进类固醇解毒(即甲基化,转氨基化)。


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